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KMID : 0984720060380030174
Infection and Chemotherapy
2006 Volume.38 No. 3 p.174 ~ p.178
A Case of Rhabdomyolysis in a Patient with Plasmidium vivax Malaria Treated with Hydroxychloroquine
Jung Se-Jin

Kim Yeon-A
Ghil Jee-Hoon
Ku Nam-Su
Kim Jun-Hyung
Park Yoon-Sun
Kim Myung-Soo
Kim Young-Keun
Shin So-Youn
Choi Jun-Yong
Kim June-Myung
Abstract
Rhabdomyolysis is a potentially life-threatening syndrome resulting form the breakdown of skeletal muscle fibers with leakage of muscle contents into the circulation. Rhabdomyolysis may complicate many disease states. In some cases, patients with malaria may be complicated with rhabdomyolysis. Also hydroxychloroquine may induce myopathy and rhabdomyolysis. But there is no case report of rhabdomyolysis after use of hydroxychloroquine in a Korean patient with Plasmodium vivax malaria. Recently we experienced a patient who developed rhabdomyolysis 20 days after starting therapy with hydroxychloroquine for the treatment of P. vivax malaria. We report the case with the review of the literature.
KEYWORD
Rhabdomyolysis, Plasmidium vivax, Malaria, Hydroxychloroquine
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